Hepatoprotective Activity of Tamarind Indica and Homalomena Aromatica in Rats

The study was performed to assess and compare the hepatoprotective activities of Tamarind indica and Homalomena aromatica in acute and chronic animal models. In this study, animals were divided into 5 groups containing 6 rats in each group. Carbon tetrachloride was used to induce liver injury in rats and Silymarin was used as the standard drug. The estimation of liver weight and blood parameters consist of serum protein, total bilirubin, serum glutamic oxalate transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT), alkaline phosphates and albumin to globulin ratio were performed. SGOT in (91.3±2.1) acute and (94.6±1.9) chronic models and SGPT in (101.3±2.8) acute and (111.3±2.8) chronic models was high in homalomena aromatic treated group when compared to tamarind indica treated group. However, serum protein, SGPT, ALP and albumin: globulin ratio of homalomena aromatic and tamarind indica treated groups in both acute and chronic models were found to be (P<0.05) significant. The finding of this study suggest that both the extracts i.e., tamarind indica and homalomena aromatica in acute and chronic animal models have similar hepatoprotective activities.